association of angiotensin converting enzyme gene polymorphism and indian army triathletes performance

نویسندگان

shweta shenoy department of sports medicine & physiotherapy, guru nanak dev university, amritsar, punjab, india

suparna tandon department of sports medicine & physiotherapy, guru nanak dev university, amritsar, punjab, india

jaspal sandhu department of sports medicine & physiotherapy, guru nanak dev university, amritsar, punjab, india

amarjeet bhanwer department of sports medicine & physiotherapy, guru nanak dev university, amritsar, punjab, india

چکیده

purpose it is well known that the effects of exercise training gives inter individual differences which might be due to genetic diversity. this study aims to explore the probable relation between angiotensin converting enzyme (ace) alleles and physical fitness parameters in elite athletes. methods twenty-nine national level indian army triathletes who volunteered for the study were taken as subjects and 101 healthy age matched control group subjects were taken for comparison of genotype frequencies. the following parameters were checked in triathletes: blood pressure, body mass index, vo2 max, muscular endurance, flexibility and power. dna was extracted from blood using standard phenol-chloroform method. genotyping was done using pcr specific for ace (i/d) polymorphism, followed by agarose gel electrophoresis method. variation of the parameters among different genotypes was compared. genotype frequencies of triathletes were compared with the control group as well. results no difference was observed between fitness parameters of three genotype groups’ triathletes, while the frequency of i allele was found to be very high in triathletes compared with the control group. conclusion it can be concluded that there might be a positive association between i allele of ace gene and endurance.

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عنوان ژورنال:
asian journal of sports medicine

جلد ۱، شماره ۳، صفحات ۱۴۳-۱۵۰

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